![]() Possible causes of a low MPV can also vary depending on the platelet count.Causes of Low Mean Platelet Volume (MPV).Pre-eclampsia (toxemia of pregnancy) and HELLP syndrome.Bone marrow stimulating drugs, such as erythropoietin or thrombopoietin.Bernard-Soulier Disease (giant platelet syndrome).(The term petechiae refers to small red marks on the skin (small bruises) which don't blanch when you press on them.) Purpura is the medical term for a bruise, usually a fairly large bruise. The root word "thrombo" refers to clot (the function of platelets) and "penia" refers to deficiency, so thrombocytopenia refers to a deficiency of platelets. It is doctor lingo for "we don't have a clue" why it occurs. Idiopathic is a term used to describe a condition of unknown cause. The condition idiopathic thrombocytopenic purpura has a long name, but looking at each of the terms in ITP makes this easier to understand. Idiopathic thrombocytopenic purpura (ITP): ITP is a condition in which the immune system destroys platelets.In response, your bone marrow releases more of the young, larger platelets, and your MPV rises.Įvaluating a high MPV is most helpful in determining the cause of a low platelet count, and the most common cause is "destruction," or the platelets being destroyed in some way, such as by antibodies you produce (see ITP below).Ī high MPV with a high platelet count, in contrast, is often due to primary or essential thrombocytosis (a condition in which the body produces too many platelets, often due to a genetic mutation), or cancer.Ī high MPV with a normal platelet count suggests conditions such as hyperthyroidism, or chronic myelogenous leukemia.Ĭonditions that may cause an elevated MPV include : If you have had a procedure such as major surgery, your body is using up platelets to repair the cuts to the blood vessels. A CBC reveals important information about the number of different blood cells in the body.Ĭauses of a High Mean Platelet Volume (MPV)Ī high MPV is usually a sign that there are more young platelets circulating in your bloodstream. The mean platelet volume (MPV) blood test is typically part of a complete blood count (CBC) test. High or low platelet levels can be a sign of a severe condition. Platelets help the blood heal wounds and prevent excessive bleeding. Mean platelet blood volume is a blood test that measures the average number of platelets in the blood. In rare cases, platelets can be affected by a genetic defect.Why test for Mean Platelet Volume (MPV) at Symbion VIP Diagnostics, Ahmedabad ? Decreased platelet levels may be caused by a women's menstrual cycle or pregnancy. Living in high altitudes, strenuous physical activity, and certain drugs, such as birth control pills, may cause an increase in platelet levels. There are many factors that can affect the results of your MPV blood test. ![]() ![]() It may also indicate marrow hypoplasia, a disorder that causes a decrease in blood cell production. What are some of the causes of low Mean Platelet Volume (MPV)?Ī low MPV can indicate exposure to certain drugs that are harmful to cells. It usually starts after the 20th week of pregnancy. Preeclampsia, a complication in pregnancy that causes high blood pressure. Myeloproliferative disease, a type of blood cancer Thrombocytopenia, a condition in which your blood has a lower than normal number of platelets Depending on your platelet count and other blood measurements, an increased MPV result can indicate: MPV results, along with platelet counts and other tests, can provide a more complete picture of the health of your blood. What are some of the causes of high Mean Platelet Volume (MPV)? A platelet count measures the total number of platelets you have. A test called a platelet count is often included with an MVP test. Why is this analysis important?Īn MPV blood test is used to help diagnose or monitor a variety of blood-related conditions. The test can help diagnose bleeding disorders and diseases of the bone marrow. An MPV blood test measures the average size of your platelets. Platelets are small blood cells that are essential for blood clotting, the process that helps you stop bleeding after an injury. Mean Platelet Volume (MPV) What is Mean Platelet Volume (MPV)?
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